Endocrine Abstracts

Objective: One of the ways to predict nephrolithiasis, which is one of the surgical indications in patients with asymptomatic primary hyperparathyroidism, is to detect hypercalciuria. A calcium excretion of >400 mg/day in 24-hour urine, >4 mg/kg/day calcium excretion in 24-hour urine or a fractionated calcium excretion (FECa) >0.010 guide us in the detection of hypercalciuria and therefore nephrolithiasis. The aim of our study is which of these three tests is more ...

Objective: Subclinical Cushing’s Syndrome is defined as the condition of detecting moderate autonomic cortisol secretion, and it has many conditions such as diabetes, obesity, hypertension, osteoporosis, cardiovascular events, thromboembolic disease, dyslipidemia and immunosuppression comorbidities and with mortality having a relationship shown. Declared a global pandemic COVID-19 infection rapidly spreading with symptoms characterize andmortal one who can watch is a dise...

Introduction: Thyroid nodules are common in population. High resolution ultrasound and fine needle aspiration biopsy (FNAB) are advised as the first line diagnostic methods. Bethesda classification system is used to provide standardization of cytologic reports. We aimed to evaluate ultrasound guided FNAB results in a mild-to-moderate iodine deficient city of Turkey.Methods: The patients (n=520), who underwent FNAB between December 2011 and Decem...

Heterophilic antibodies are well-known interferent factors affecting most immunoassays. However, they have been poorly evaluated in routine clinical practice. Definition of Subclinical Cushing’s Syndrome (SCs) has been arbitrary and prevalence has shown significant variations related with the diversity of the diagnostic tests. In most of the guidelines a low or suppressed corticothropin (ACTH) level has been suggested as an important predictor of SCs. Here, we sought to i...

Background and aim: Although insulinoma typically causes fasting hypoglycemia, postprandial hypoglycemia occasionally reported in these patients. We aimed to report a rare case of insulinoma who atmitted to outpatient clinic with postprandial hypoglycemia.Case report: A 31-year-old woman was admitted to outpatient clinic with postprandial hypoglycemia. Capillary blood glucose levels were found 25 and 27 mg /dl during typical hypoglycemic symptoms such as...

We report an 18 years old female with hepatomegaly and elevated liver function tests. She had been diagnosed with Type 1 diabetes mellitus when she was 13 years old. She was referred to our division because of diabetic ketoacidosis. Evaluation of her previous records revealed the presence of liver function abnormalities for 4 months. At physical examination she had an enlarged liver. A1c level was 13%. She was treated initially with intravenous insulin. Following the achieveme...

Previous gestational diabetes mellitus (pGDM) is associated with insulin resistance which is a well-known risk factor for atherosclerotic diseases. Mean platelet volume (MPV) is an indicator of platelet activation which plays a crucial role in pathogenesis of atherosclerosis.One hundred and five consecutive women with pGDM and 40 healthy women with normal previous pregnancies were included in the study. At the time of enrollment, anthropometric measureme...

It has been shown that women with previous GDM more likely developed metabolic syndrome (MS). This study aimed to determine predictors of the later development of MS in women with previous GDM.One hundred sixty-four consecutive women with previous GDM were evaluated after a mean follow-up of 40.54 months from index pregnancy. Sixty-five lean women with negative screening for GDM were included as a control group. Data regarding antenatal and peripartum ch...

Background and aim: Hyperprolactinemia may associate with insulin resistance. This fact has been determined by many studies with methods which show insulin sensitivity. In this study we aimed to search insulin resistance with golden standard euglycemic hyperinsulinemic clamp technique on hyperprolactinemic patients.Subjects and methods: This study was performed in Endocrinology Department of Dicle University. Sixteen patients with microprolactinoma (mean...

Background: Proximal tubule dysfunction in Fanconi syndrome causes impaired reabsorbtion of amino acids, glucose, urate and phosphate, which leads to hypophosphatemic osteomalcia. Adefovir and tenofovir are two nucleoside reverse transcriptase inhibitors, which are used for treatment of patients with hepatitis B infection. Although these drugs are well tolerated with few side effects, patients may rarely suffer from drug-induced Fanconi syndrome and hypophosphatemic osteomalac...